Women, ages 50 to 79, enrolled at centers across the country between 1993 and 1998. Almost 17,000 women with an intact uterus participated in an estrogen plus progestin therapy trial. About 10,700 women whod had a hysterectomy (surgical removal of the uterus) participated in an estrogen-alone therapy trial. About 81% continued follow-up after the planned end of the trials. Findings from a comprehensive analysis of 13 years of cumulative data were published on October 2, 2013, in the Journal of the American Medical Association.
For the original version including any supplementary images or video, visit http://www.nih.gov/researchmatters/october2013/10282013hormone.htm
Hormone therapy, calcium may lower fracture risk
During an average one-year period, they calculated that 11 out of 10,000 women taking both hormones and calcium and vitamin D would suffer a hip fracture, compared to 22 per 10,000 using neither. However, the combination treatment had no effect on women’s bone mineral density – a reflection of osteoporosis and fracture risk, Wactawski-Wende and her team reported in the journal Menopause. Some previous studies have suggested that vitamin D may protect against fractures less by strengthening bones than by improving muscle strength and thereby reducing falls, but others have not found the same effect. Hormone therapy has become less common since WHI data linked hormone use to heart disease, stroke and breast cancer, though it’s still considered the most effective treatment for some symptoms of menopause, such as hot flashes. Curtis, who wasn’t involved in the new research, said she thinks the pendulum initially swung too far away from hormone therapy, and that doctors are coming to realize it may still help some women.
For the original version including any supplementary images or video, visit http://www.reuters.com/article/2013/06/28/us-hormone-therapy-idUSBRE95R0YN20130628
Fresh Look At Hormone Therapy For Menopause Symptoms
6. Divigel [package insert]. Minneapolis, MN: Upsher-Smith Laboratories, Inc.; 2012. 7. EstroGel [package insert]. Herndon, VA: ASCEND Therapeutics, Inc.; 2009.
For the original version including any supplementary images or video, visit http://www.imperialvalleynews.com/index.php/news/health/5878-fresh-look-at-hormone-therapy-for-menopause-symptoms.html